A spotlight on dosage and subject selection for effective neuroprotection: exploring the central role of mitochondria Mitrofanis, John*; Stone, Jonathan; Hamblin, Michael R.; Magistretti, Pierre; Benabid, Alim-Louis; Jeffery, Glen Author Information Neural Regeneration Research 20(4):p 1081-1082, April 2025. | DOI: 10.4103/NRR.NRR-D-24-00222 Neurons are notoriously vulnerable cell types. Even the slightest change in their internal and/or external environments will cause much distress and dysfunction, leading often to their death. A range of pathological conditions, including stroke, head trauma, and neurodegenerative disease, can generate stress in neurons, affecting their survival and proper function. In most neural pathologies, mitochondria become dysfunctional and this plays a pivotal role...